Award

National Institute on Drug Abuse 5R01DA062186-02

Optimizing methadone treatment strategies for opioid use disorder in the era of fentanyl

Recipient

Brown University, Providence, RI

Award Amount

$855,061.00

Ceiling

$855,061.00

Awarded

May 19, 2026

Identifier

5R01DA062186-02

A research project funded by the National Institute on Drug Abuse to study methadone treatment strategies for opioid use disorder in the context of fentanyl use, focusing on treatment retention and overdose outcomes in Rhode Island.

Description

This project aims to evaluate the effectiveness and safety of different methadone treatment strategies, including dosing and expanded take-home flexibilities associated with the COVID-19 pandemic, on treatment retention and overdose outcomes in a cohort of approximately 10,000 patients in Rhode Island. The study will leverage electronic health records and state administrative data to inform best practices for patients using fentanyl.

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