Award
National Institute of General Medical Sciences 5R16GM150784-04
The Impact of Disrupting Sensory Innervation on Tibial Bone Mass
Recipient
University of New England, Biddeford, ME, United States
Award Amount
$177,500.00
Ceiling
$177,500.00
Awarded
July 16, 2026
Identifier
5R16GM150784-04
A research project funded by the National Institute of General Medical Sciences to study how disrupting sensory innervation affects tibial bone mass, potentially identifying new risk factors for tibial fractures.
Description
This project explores the role of saphenous nerve injury in controlling tibial bone mineral density through sensory nerves. It aims to characterize the impact of saphenous nerve transection on tibial bone mass and innervation, and assess the contribution of sensory nerve fiber subtypes on tibial bone mass through chemical ablation of peptidergic and non-peptidergic sensory neurons.