Award
National Institute of General Medical Sciences 5R35GM142421-05
Development of Genetic Sensors and Circuits for Creating Novel Cellular Behaviors
Recipient
University of North Texas, Denton, TX
Award Amount
$360,055.00
Ceiling
$360,055.00
Awarded
August 07, 2025
Identifier
5R35GM142421-05
Research project to develop genetic sensors and circuits for biomedical applications, including environmental monitoring of toxic pollutants.
Description
The proposed research aims to advance the engineering of organisms for biomedical uses by developing design principles for regulators from protein families, genetic sensors for signals, and genetic circuits addressing biomedical problems. The project includes engineering transcriptional regulators as modular biosensors and exploring hybrid regulators for novel circuit designs, including monitoring toxic pollutants in food and water.