Award
National Eye Institute 5R00EY033909-04
The role of neuronal activity on retinal angiogenesis and blood-retina barrier (BRB) maturation
Recipient
Cleveland Clinic Lerner COM-CWRU
Award Amount
$248,999.00
Ceiling
$248,999.00
Awarded
May 13, 2026
Identifier
5R00EY033909-04
The award funds research to understand how neuronal activity influences retinal blood vessel development and barrier formation, aiming to inform treatments for eye diseases.
Description
This project explores how cholinergic and glutamatergic neuronal activities regulate retinal angiogenesis and blood-retinal barrier maturation using genetic models. The goal is to develop novel therapeutic interventions for degenerative diseases and ischemic retinopathies of the eye.