Award
NIH Reporter #1R01DK144183-01A1
Novel approach to target Na,K-ATPase to slow renal cystogenesis
Recipient
University of Kansas Medical Center
Award Amount
$334,627.00
Ceiling
$334,627.00
Awarded
August 28, 2026
Identifier
1R01DK144183-01A1
Award for research on targeting Na,K-ATPase to slow renal cystogenesis in ADPKD cells using ouabain derivatives as therapeutics.
Description
The project aims to define the molecular mechanisms responsible for increased affinity of NKA for ouabain in ADPKD cells and establish proof-of-principle for ouabain derivatives as targeted therapeutics.