Award
National Institute of Allergy and Infectious Diseases 1F31AI188668-01A1
Roles for Ets1 in thymic selection and CD8αα IEL development
Recipient
University of Chicago, Chicago, IL, United States
Award Amount
$49,538.00
Ceiling
$49,538.00
Awarded
August 13, 2025
Identifier
1F31AI188668-01A1
Research project funded by NIAID to study the role of Ets1 in thymic selection and CD8αα IEL development, with implications for autoimmune diseases.
Description
This research investigates the role of the transcription factor Ets1 in thymic selection and the development of CD8αα intraepithelial lymphocytes (IELs). The study aims to elucidate how Ets1 influences positive selection, clonal deletion, and IEL function, with potential implications for autoimmune disease understanding.