Award
National Institute of Neurological Disorders and Stroke 1R01NS148198-01
Heterosynaptic mechanisms driving elevated synaptic inhibition and plasticity impairments following ischemia.
Recipient
University of Colorado Denver, Aurora, CO
Award Amount
$473,860.00
Ceiling
$473,860.00
Awarded
May 07, 2026
Identifier
1R01NS148198-01
Research project funded by NINDS to study synaptic inhibition and plasticity impairments after ischemia, aiming to improve cognitive outcomes post-cardiac arrest.
Description
This project focuses on the mechanisms of synaptic inhibition and plasticity impairments following ischemia, with implications for cognitive deficits after cerebrovascular injury. The research aims to investigate changes in inhibitory synaptic transmission that contribute to synaptic dysfunction and memory impairments after cardiac arrest, using an in vivo rodent model and various experimental techniques to identify novel therapeutic targets.