Award

NIH Reporter #5R44GM146506-03

Stabilization of therapeutic microbes for inclusion in a liquid matrix for delivery to the intestines

Recipient

VITAKEY, INC.

Award Amount

$607,851.00

Ceiling

$607,851.00

Awarded

September 02, 2026

Identifier

5R44GM146506-03

Development of a stable probiotic formulation for enteral feeding patients to prevent antibiotic-associated diarrhea, including evaluation in mouse models and aiming for clinical efficacy and long-term shelf stability.

Description

This project involves customizing and further developing an oral delivery platform formulation for stabilizing microbes in a liquid for use by patients on enteral feeding (EF) nutritional formula. The goal is to create a probiotic formulation that maintains stability and viability in EF formulas and upon consumption, addressing issues of shelf stability, dosage consistency, and contamination risk.

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