Award
National Institute on Aging 4R01AG078677-02
Investigating the role and therapeutic potential of the alpha5beta1 integrin in risk factors for COVID-19-associated cognitive impairment
Recipient
Tulane University of Louisiana
Award Amount
$721,756.00
Ceiling
$721,756.00
Awarded
April 06, 2026
Identifier
4R01AG078677-02
The project aims to demonstrate that experimental vascular dementia worsens COVID-19 morbidity and cognitive decline, evaluate the therapeutic potential of integrin α5β1 inhibition, and elucidate the signaling mechanisms involved.
Description
This project investigates the mechanistic role of integrin α5β1 in COVID-19-related cognitive impairment in the context of vascular dementia, with a focus on therapeutic inhibition strategies.