Award
NIH Reporter #5R01AI189984-02
Crosstalk of Immune Dysregulation and Impaired Wound Healing in inherited STAT4-mediated Autoinflammatory Disease
Recipient
Not specified
Award Amount
$398,959.00
Ceiling
$398,959.00
Awarded
December 16, 2025
Identifier
5R01AI189984-02
NIH awarded a grant to study STAT4's role in autoinflammatory disease, focusing on immune dysregulation and wound healing using cellular and animal models.
Description
The project focuses on understanding the role of STAT4 in autoinflammatory disease, with specific aims to elucidate mechanisms of immune dysregulation, neovascularization, and wound healing. The award is managed by the NIH, with a focus on immunology and pediatric health. The project involves in vitro and in vivo studies, including patient-derived induced pluripotent stem cells and murine models.