Award
National Institute of Allergy and Infectious Diseases 1U01AI195536-01
Role of PBP4 in mediating antibiotic resistance and pathogenesis of Staphylococcus aureus
Recipient
University of Maryland Baltimore
Award Amount
$634,247.00
Ceiling
$634,247.00
Awarded
July 09, 2026
Identifier
1U01AI195536-01
The award supports research on the role of PBP4 in antibiotic resistance and pathogenesis of Staphylococcus aureus, focusing on mechanisms of resistance, cell wall changes, and bacterial virulence.
Description
This project aims to elucidate the role of PBP4 in mediating broad-spectrum β-lactam resistance and bacterial pathogenesis in Staphylococcus aureus. The research will explore the mechanisms of resistance, how PBP4 alters cell wall composition, and its impact on bacterial virulence.