Award
Eunice Kennedy Shriver National Institute of Child Health and Human Development 5R44HD100269-03
Synthetic PreImplantation Factor (sPIF) plus hypothermia to treat neonatal brain injury
Recipient
Mason
Award Amount
$816,664.00
Ceiling
$816,664.00
Awarded
May 01, 2025
Identifier
5R44HD100269-03
Award for research on combining synthetic PreImplantation Factor and hypothermia to treat neonatal brain injury, focusing on efficacy testing and functional assessments.
Description
Project involves testing the efficacy of hypothermia plus a novel immunomodulatory compound (sPIF) for neonatal brain injury. The project aims to complete dose-response studies, behavioral and cognitive tests, and functional MRI. The project is in response to an urgent need for effective therapies for hypoxic-ischemic encephalopathy (HIE).