Award
National Institute of Diabetes and Digestive and Kidney Diseases 5R01DK131558-05
Unraveling the homeostatic and hedonic circuits underlying feeding behavior and obesity
Recipient
Monell Chemical Senses Center, Philadelphia, PA, United States
Award Amount
$449,462.00
Ceiling
$449,462.00
Awarded
July 18, 2025
Identifier
5R01DK131558-05
Research project funded by NIDDK to study how homeostatic and hedonic brain circuits interact to promote overeating and obesity, aiming to develop prevention and treatment strategies.
Description
The drive to eat is mediated by activity in homeostatic (nutrient need, hunger) and hedonic (pleasure, reward) neural circuits in the brain. This project aims to identify neural intersection points of homeostatic and hedonic circuits and develop biomarkers for overeating and obesity risk. The research focuses on understanding neural circuits involved in feeding behavior and obesity development.