Award
NIH Reporter #1K99AG095272-01
Structure determination of amyloid oligomers and amyloid-TREM2 complexes
Recipient
University of California Los Angeles
Award Amount
$126,063.00
Ceiling
$126,063.00
Awarded
August 04, 2026
Identifier
1K99AG095272-01
The project aims to investigate the structures of amyloid oligomers and their complexes with TREM2 to understand Alzheimer's Disease pathogenesis and develop structure-based drug design targets.
Description
This grant supports research on amyloid structures related to Alzheimer’s Disease, utilizing advanced cryoEM and X-ray crystallography techniques to elucidate molecular interactions involved in disease progression.