Award
National Institute of Allergy and Infectious Diseases 5F31AI181528-02
Assessing the role of SP140 in enhanced resistance to Cryptococcus neoformans
Recipient
University of Minnesota
Awarded
August 14, 2025
Identifier
5F31AI181528-02
Research project awarded to study SP140's role in resistance to Cryptococcus neoformans, involving mouse model development and immune response analysis during HIV coinfection.
Description
The project focuses on the role of SP140 in resistance to Cryptococcus neoformans. The research involves developing a mouse model that mimics human necrotic granulomas. The project aims to understand immune responses and mechanisms of granuloma breakdown during HIV coinfection. The funding agency is the National Institute of Allergy and Infectious Diseases (NIAID).