Award
National Heart, Lung, and Blood Institute 5R01HL060190-20
Metabolic reprogramming of smooth muscle cells in pulmonary hypertension
Recipient
University of Miami
Award Amount
$628,894.00
Ceiling
$628,894.00
Awarded
April 27, 2026
Identifier
5R01HL060190-20
Award for research on metabolic reprogramming of smooth muscle cells in pulmonary hypertension, funded by NIH and involving advanced methodologies to explore therapeutic targets.
Description
The project focuses on pulmonary hypertension and metabolic reprogramming in pulmonary artery smooth muscle cells. It involves state-of-the-art methodologies including structural, biophysical, biochemical, and functional assays. The project aims to elucidate mechanisms involving mitochondrial PKG-Iα signaling as a therapeutic target. The award is multi-year, spanning from December 2025 to November 2026, and involves collaboration with the University of Miami.