Award

National Institute of Neurological Disorders and Stroke 1R21NS147149-01

Repetitive Mild TBI and Physiological Stress as Catalysts for Chronic Neurovascular Dysfunction

Recipient

University of Kentucky

Award Amount

$192,500.00

Ceiling

$192,500.00

Awarded

January 26, 2026

Identifier

1R21NS147149-01

This NIH-funded research project investigates how repetitive mild traumatic brain injuries and physiological stress contribute to chronic neurovascular dysfunction, using a mouse model to study inflammation-driven disease progression.

Description

The project focuses on the effects of repetitive mild traumatic brain injuries and physiological stress on neurovascular health. The study involves a mouse model, sleep fragmentation, and treatment with MW151. The research aims to identify inflammation-driven neurovascular dysfunction as a mechanism for disease progression. The project is funded by the NIH and involves the University of Kentucky.

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