Award
National Institute of General Medical Sciences 5R35GM143042-06
Biophysical models and mechanisms for cellular adaptation to environmental stress
Recipient
Georgia Institute of Technology, Atlanta, GA
Award Amount
$342,827.00
Ceiling
$342,827.00
Awarded
August 14, 2025
Identifier
5R35GM143042-06
This award funds research to develop computational models that explain how cells adapt physically and biochemically to environmental stresses, using interdisciplinary approaches and experimental data.
Description
The project aims to develop quantitative theory and data-driven computational models to uncover the biophysical feedback mechanisms underlying cellular adaptive response to environmental stresses. It integrates tools from statistical physics, systems biology, and experimental data analysis to construct predictive models for cell behavior, focusing on adaptation in bacterial cells and nematode worm embryos.