Award
National Heart, Lung, and Blood Institute 1F31HL168876-01A1
Deep Learning 4D flow MR Pipeline for the Automated Assessment of Aortic Hemodynamics in BAV
Recipient
Northwestern University, Chicago, IL
Award Amount
$45,629.00
Ceiling
$45,629.00
Awarded
August 30, 2025
Identifier
1F31HL168876-01A1
Award to develop a deep learning-based 4D flow MRI pipeline for assessing aortic hemodynamics in bicuspid aortic valve patients, using existing datasets and a pilot clinical study.
Description
Develop and optimize a highly accelerated deep learning-based 4D flow MRI flow acquisition, reconstruction, and preprocessing pipeline to measure aortic hemodynamics and structural measures in bicuspid aortic valve (BAV) patients. Utilize over 2300 existing 4D flow MRI datasets for evaluation and testing of a deep learning reconstruction method and fully automated preprocessing pipeline. Conduct a pilot study comparing BAV patients with aortic dilatation to healthy controls to assess clinical utility.