Award
National Institute of Diabetes and Digestive and Kidney Diseases 1R01DK142678-01A1
The molecular and physiologic effects of calcineurin inhibitors on WNK body bimolecular condensates
Recipient
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Award Amount
$769,882.00
Ceiling
$769,882.00
Awarded
April 17, 2026
Identifier
1R01DK142678-01A1
NIH R01 grant awarded to study the effects of calcineurin inhibitors on WNK body biomolecular condensates, aiming to validate WNK bodies as pharmacological targets in kidney physiology and immunosuppressant side effects.
Description
This is a NIH R01 grant opportunity focused on the effects of calcineurin inhibitors on WNK body biomolecular condensates. The project involves cellular models, mouse models, and human kidney biopsy samples. The goal is to validate WNK bodies as pharmacological targets and understand their role in kidney physiology and side effects of immunosuppressants.