National Institute of General Medical Sciences 2R15GM112121-02

Computational and biochemical screening for the discovery of molecules that stabilize ITPA clinical variants

NIH awarded a grant for research on discovering molecules that stabilize ITPA clinical variants using computational and biochemical methods, involving undergraduate researchers and multiple screening techniques.

Description

The project involves computational and biochemical screening to discover molecules that stabilize ITPA variants. It includes in silico screening, high throughput screening, biochemical assays, and molecular dynamics simulations. Undergraduate researchers will participate in various experimental steps. The award is part of NIH's efforts to address rare diseases and drug discovery.

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