Award

National Institute of Mental Health 5R01MH134870-03

Charting Positive Valence Systems Trajectories in Offspring of Depressed Mothers to Predict Internalizing Symptoms in Early Childhood

Recipient

Pennsylvania State University, The

Award Amount

$765,486.00

Ceiling

$765,486.00

Awarded

June 23, 2026

Identifier

5R01MH134870-03

A research project funded by the National Institute of Mental Health to investigate the impact of maternal depression on early childhood brain and behavioral development related to internalizing symptoms, aiming to inform targeted prevention efforts.

Description

This project studies how maternal depression affects Positive Valence Systems (PVS) trajectories in early childhood to predict internalizing symptoms. It uses a multimodal, accelerated longitudinal design with 450 children aged 4-6 at baseline, followed over 2 years, examining maternal depression effects, maternal positive emotion behaviors, and child early life adversity on PVS development.

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