Award
National Institute of Allergy and Infectious Diseases 5R03AI176361-02
Characterization of Histoplasma transcription factors using improved episomal DNA maintenance and controllable gene expression tools
Recipient
J. Craig Venter Institute, Inc.
Award Amount
$94,575.00
Ceiling
$94,575.00
Awarded
November 18, 2024
Identifier
5R03AI176361-02
The award supports research to develop genetic tools for studying gene regulation and virulence in the fungal pathogen Histoplasma capsulatum, aiming to improve understanding of its pathogenic mechanisms.
Description
This project aims to develop controllable gene expression systems and optimize episomal DNA maintenance to study gene function in Histoplasma capsulatum, a fungal pathogen causing respiratory infections. The project focuses on gene regulation during yeast-phase growth and virulence, generating mutants to study gene function.