Award
National Institute of Allergy and Infectious Diseases 5R16AI177410-02
Role of epigenetic changes in intracellular survival and replication of Legionell pneumophila
Recipient
Not specified
Award Amount
$177,183.00
Ceiling
$177,183.00
Awarded
August 20, 2025
Identifier
5R16AI177410-02
Research project awarded to study epigenetic changes affecting Legionella pneumophila survival and replication in macrophages, including DNA methylation and histone modifications, with a budget of approximately $177,183 for fiscal year 2025.
Description
This project aims to understand the role of epigenetic modifications in the survival and replication of Legionella pneumophila, focusing on DNA methylation and histone modifications in infected macrophages. It involves RNA sequencing, methylation assays, and protein interaction studies.