Award
National Institute on Aging 5U19AG074866-04
Project 2: Identify and enhance LOAD-related signatures in outbred and genetically-engineered marmosets
Recipient
University of Pittsburgh at Pittsburgh, Pittsburgh, PA, United States
Award Amount
$362,061.00
Ceiling
$362,061.00
Awarded
July 28, 2025
Identifier
5U19AG074866-04
This project aims to develop marmosets as a model for late-onset Alzheimer’s disease by assessing genetic variation, establishing statistical models, and aligning molecular markers with human data to support preclinical research and therapeutic development.
Description
Determining the early molecular and cellular events in the origins and progression of late-onset Alzheimer’s disease (LOAD) using marmoset models to integrate genetic, molecular, imaging, and behavioral data for preclinical research.