Award
National Institute of General Medical Sciences 1R35GM160071-01
Viral Biosensors of Host Post-Translational Modifications
Recipient
University of California Los Angeles
Award Amount
$420,984.00
Ceiling
$420,984.00
Awarded
July 31, 2025
Identifier
1R35GM160071-01
The project studies how viral proteins are modified by host post-translational modifications to act as molecular sensors, aiming to develop new antiviral therapies by targeting these mechanisms.
Description
This research aims to increase understanding of how viruses sense, respond, and adapt to their hosts through host-derived post-translational modifications, diversifying viral proteoforms and generating multifunctionality. Insights gained could lead to new treatment strategies for viral infections and other diseases driven by specific proteoforms.