Award
National Institute of Allergy and Infectious Diseases 5R01AI184895-02
Multivalent mRNA-based malaria vaccines
Recipient
Drexel University, Philadelphia, PA
Award Amount
$718,445.00
Ceiling
$718,445.00
Awarded
August 05, 2025
Identifier
5R01AI184895-02
This NIH grant supports research to develop multivalent mRNA vaccines targeting multiple stages of malaria parasites to improve vaccine efficacy and durability.
Description
The project focuses on evaluating mRNA technology for delivery of a malaria vaccine designed to elicit responses against multiple parasite stages. It aims to optimize mRNA vaccines targeting P. falciparum and P. vivax to induce durable, antibody-mediated, and cell-mediated immune responses, with the goal of developing a true multi-stage malaria vaccine.