Award
National Heart, Lung, and Blood Institute 5R01HL114948-14
Early cardiac progenitors
Recipient
J. DAVID GLADSTONE INSTITUTES, SAN FRANCISCO, CA, UNITED STATES
Award Amount
$718,069.00
Ceiling
$718,069.00
Awarded
July 07, 2026
Identifier
5R01HL114948-14
Research project funded by the National Heart Lung and Blood Institute to study early heart development and congenital heart defects using multiomics, live imaging, and genome editing.
Description
This project aims to understand early heart development and congenital heart defects through analysis of gene expression, chromatin states, live imaging, and genome engineering. The research focuses on decoding transcription factor functions, defining chamber-specific gene regulatory networks, and studying human cardiac progenitors with a focus on hypoplastic left heart syndrome.