Award
NIH Reporter #5K99AG088296-02
Understanding the relationship between cortical hyperexcitability and the progression of FTD/ALS pathology and behavioral deficits in mice
Recipient
Massachusetts General Hospital
Award Amount
$112,070.00
Ceiling
$112,070.00
Awarded
July 31, 2025
Identifier
5K99AG088296-02
NIH grant awarded to Massachusetts General Hospital to study the mechanisms of Frontotemporal Dementia (FTD) and Amyotrophic Lateral Sclerosis (ALS) pathology progression in mice, focusing on neuronal hyperexcitability and its impact on disease progression and behavior, using advanced imaging and neuromodulation techniques.
Description
This NIH grant supports research aimed at understanding and developing therapies for FTD/ALS by investigating neuronal hyperexcitability and circuit dysfunction using advanced imaging and neuromodulation techniques. The project includes comprehensive training and mentorship to foster an independent research career.