Award
NIH Reporter #5R01DK126892-04
The cellular molecular regulation of differing mechanisms of insulin resistance.
Recipient
Howard University
Award Amount
$345,992.00
Ceiling
$345,992.00
Awarded
August 23, 2025
Identifier
5R01DK126892-04
Research project funded by the National Institute of Diabetes and Digestive and Kidney Diseases to study different mechanisms of insulin resistance using animal models, aiming to better understand and potentially treat prediabetes.
Description
This project focuses on understanding mechanisms of insulin resistance through animal models, with potential for targeted therapeutic interventions based on the specific model of insulin resistance. The study aims to develop mouse models of hepatic insulin resistance related to high androgen, high fat diet, and high fructose diet, using knockout mice to examine intersecting pathogenic mechanisms.