Award
National Institute of Allergy and Infectious Diseases 11317810
Blocking pathogenic anti-donor antibody responses
Recipient
New York University School of Medicine
Award Amount
$76,780.00
Ceiling
$76,780.00
Awarded
March 30, 2026
Identifier
11317810
NIH-funded project by New York University School of Medicine to develop targeted antibody therapies to prevent transplant rejection caused by donor-specific antibodies.
Description
The project focuses on developing antibody-based therapies to address transplant rejection driven by donor-specific antibodies (DSAs). It involves epitope mapping, structural analysis, and engineering of recombinant antibodies. The funding is provided by the NIH, specifically the National Institute of Allergy and Infectious Diseases (NIAID). The project aims to develop targeted immune therapies to mitigate DSA-mediated transplant rejection without relying on broad immunosuppression.