Award
National Institute of Neurological Disorders and Stroke 1R21NS130385-01A1
Epilepsy after penetrating brain injury
Recipient
University of Virginia, Charlottesville, VA, United States
Award Amount
$444,125.00
Ceiling
$444,125.00
Awarded
September 21, 2023
Identifier
1R21NS130385-01A1
This award funds research on epilepsy development after penetrating brain injury using a rat model, focusing on the impact of toxic metal fragments like copper and lead on neurological outcomes.
Description
Brain trauma is a common cause of epilepsy, especially trauma from penetrating injuries (e.g., gunshot wounds). This project uses a rat model of penetrating brain injury to study factors contributing to epilepsy and long-term neurological outcomes, focusing on the role of toxic metal fragments like copper and lead. The study aims to understand how exposure duration to these metals influences damage and epilepsy development, with implications for clinical care of injury survivors.