National Cancer Institute 11457454

CD28-KITv CAR T cells with PD-1 dominant negative receptor

Award for development and clinical testing of next-generation CAR T-cell therapies targeting solid tumors, funded by the National Cancer Institute.

Description

This project involves the development and clinical testing of next-generation CAR T-cell therapies targeting solid tumors, including strategies for tumor infiltration, immune checkpoint blockade, and safety mechanisms. The project is funded by the National Cancer Institute and involves translational research with a focus on mesothelioma and other solid tumors.

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