Award
NIH Reporter #5R35NS143000-02
The Developmental Transition of Neural Stem Cell Niches in the Human Brain
Recipient
University of California, San Francisco
Award Amount
$1,178,168.00
Ceiling
$1,178,168.00
Awarded
August 25, 2026
Identifier
5R35NS143000-02
NIH awarded a multi-year research project to Arturo Alvarez-Buylla at UCSF to study neural stem cell niches in the human brain, focusing on neurogenesis and gliogenesis using advanced molecular and imaging techniques.
Description
The project aims to investigate neural progenitor cells and mechanisms of cellular amplification in the human brain, focusing on the caudal ganglionic eminence (CGE) and its role in neurogenesis and gliogenesis. The work involves multi-omics, spatial transcriptomics, electron and light microscopy. The project is funded by NIH (RFA-NS-22-038) and is a multi-year award from 2026 to 2033. The project is led by Arturo Alvarez-Buylla at the University of California, San Francisco.