Award
National Institute on Aging 5R21AG086905-02
Pain in the Elderly: Role of Hyperalgesic Priming
Recipient
University of California, San Francisco
Award Amount
$246,000.00
Ceiling
$246,000.00
Awarded
May 07, 2025
Identifier
5R21AG086905-02
Research project awarded to study pain mechanisms in elderly, focusing on hyperalgesic priming and potential therapeutics, funded by NIH/NIA.
Description
This is a research project funded by the NIH/NIA focusing on pain mechanisms in the elderly, specifically hyperalgesic priming related to systemic inflammation and mitochondrial dysfunction. The project involves multiple aims including establishing nociceptor plasticity in aged rats, identifying underlying mechanisms, and testing potential therapeutics. The project emphasizes personalized pain management considering sex differences.