Award
National Institute of General Medical Sciences 5R01GM155335-03
Noncanonical roles of Bim in heat shock-induced cell death
Recipient
University of TX MD ANDERSON CAN CTR, Houston, TX, United States
Award Amount
$490,122.00
Ceiling
$490,122.00
Awarded
June 03, 2026
Identifier
5R01GM155335-03
Research project investigating the role of the protein Bim in regulating lysosomal trafficking and positioning to understand mechanisms of heat shock-induced cell death and related pathologies.
Description
This project aims to characterize the noncanonical role of Bim in endolysosomal trafficking, permeabilization, and exocytosis during heat shock-induced cell death, with implications for understanding heat-related pathologies and potential therapeutic targets.