Award
National Institute of Allergy and Infectious Diseases 5K08AI148584-05
The Transmission Biology of Mycobacterium Tuberculosis
Recipient
WEILL MEDICAL COLL OF CORNELL UNIV, NEW YORK, NY, UNITED STATES
Award Amount
$194,860.00
Ceiling
$194,860.00
Awarded
May 20, 2025
Identifier
5K08AI148584-05
A research project funded by NIAID to study the transmission biology of Mycobacterium tuberculosis by investigating bacterial survival mechanisms during aerosolization to develop transmission-blocking therapies.
Description
This five-year training grant aims to develop an independent academic career by identifying bacterially-encoded determinants that facilitate successful transmission through survival in air. The project involves exposing laboratory and clinical strains of Mtb to air-drying stress and analyzing effects on metabolism and cellular integrity, utilizing CRISPRi gene silencing.