Award
National Cancer Institute 5R01CA287114-02
Rewiring T cell exhaustion with immune checkpoint blockade therapy
Recipient
Sanford Burnham Prebys Medical Discovery Institute
Award Amount
$674,996.00
Ceiling
$674,996.00
Awarded
August 05, 2025
Identifier
5R01CA287114-02
This NIH grant supports research on immune checkpoint blockade therapy targeting T cell exhaustion in malignant melanoma, aiming to develop novel therapeutic antibodies.
Description
The project aims to identify mechanisms underlying immune responses to checkpoint blockade therapy in malignant melanoma, focusing on T cell regulation and immunotherapy strategies.