Award
National Institute of Allergy and Infectious Diseases (NIAID) 5R01AI175711-04
Coordinated responses to host-derived stresses in C. neoformans
Recipient
Duke University
Award Amount
$387,087.00
Ceiling
$387,087.00
Awarded
January 14, 2026
Identifier
5R01AI175711-04
NIH research grant awarded to Duke University to study microbial adaptation and pathogenesis in Cryptococcus neoformans, focusing on host-derived stresses and environmental pH responses.
Description
The project explores how microorganisms adapt to infected hosts, focusing on the fungal pathogen Cryptococcus neoformans. It aims to identify microbial cellular processes that can be targeted for intervention, especially responses to environmental pH. The research involves transcriptomic, proteomic, and genetic techniques to understand microbial adaptation and pathogenesis.