Award
National Center for Advancing Translational Sciences 1R43TR005424-01
A Novel Approach to Eliminate Length Impurities for High-Quality mRNA Production
Recipient
Cistern Biologics, Inc.
Award Amount
$349,746.00
Ceiling
$349,746.00
Awarded
July 17, 2025
Identifier
1R43TR005424-01
Award to develop a high-purity mRNA production platform eliminating length impurities to improve therapeutic safety and efficacy.
Description
This project aims to develop a production platform for contaminant-free mRNA synthesis, focusing on eliminating impurities such as dsRNA, LRNA, and stRNA, to enhance therapeutic safety and efficacy.