Award
National Institute of Arthritis and Musculoskeletal and Skin Diseases 5R01AR068067-08
Erythrocyte-derived particles for near infrared phototherapy of port wine stains.
Recipient
University of California Riverside
Award Amount
$444,406.00
Ceiling
$444,406.00
Awarded
March 19, 2026
Identifier
5R01AR068067-08
The project aims to develop and evaluate erythrocyte-derived optical micro-particles enriched with cholesterol for use with pulsed near infrared laser irradiation as a new treatment for port wine stains, a congenital skin disease. The research includes fabrication, characterization, biodistribution studies, and therapeutic efficacy evaluation in animal models.
Description
This project focuses on developing erythrocyte-derived micro-particles doped with indocyanine green for targeted laser therapy of port wine stains, including animal and transgenic mouse models to optimize treatment parameters.