Award
National Institute on Aging 1R21AG083451-01A1
An investigation of the response of preclinical mouse models of dementia to adropin therapy
Recipient
Saint Louis University
Award Amount
$416,625.00
Ceiling
$416,625.00
Awarded
April 12, 2024
Identifier
1R21AG083451-01A1
Research grant to study the effects of adropin therapy on cognitive decline in mouse models of dementia, aiming to explore its potential as a treatment for neurodegenerative diseases.
Description
This project explores a novel protein, adropin, which may prevent or delay severe neurodegenerative conditions associated with aging and Alzheimer’s disease. The research aims to determine whether low adropin levels accelerate cognitive decline and if synthetic adropin peptide administration can prevent or reverse cognitive impairment in mouse models.