Award
Vanderbilt University Medical Center 4RF1AG085287-03
Reducing Perioperative Oxidative Stress to Prevent Postoperative Chronic Pain Following Total Knee Arthroplasty
Recipient
Vanderbilt University Medical Center
Award Amount
$2,526,074.00
Ceiling
$2,526,074.00
Awarded
September 18, 2025
Identifier
4RF1AG085287-03
NIH grant awarded to Vanderbilt University Medical Center for a study on antioxidant intervention to reduce chronic pain after total knee arthroplasty in older adults.
Description
This is a NIH grant project focused on testing whether an antioxidant intervention (glycine + N-acetylcysteine) can reduce long-term pain outcomes after total knee arthroplasty in older adults. The project involves a randomized, placebo-controlled trial with multiple follow-up assessments.