Award
NIH Reporter #5F31HD120042-02
Regulation of Argonaute Nuclear Import in Mediating Transgenerational Fertility
Recipient
Not specified
Award Amount
$50,114.00
Ceiling
$50,114.00
Awarded
July 27, 2026
Identifier
5F31HD120042-02
This NIH-funded project investigates the molecular mechanisms of Argonaute protein nuclear import and its role in transgenerational fertility using advanced molecular biology techniques.
Description
The project aims to determine the molecular mechanism of Argonaute protein small RNA-loading and nuclear import. The research will involve CRISPR editing, small RNA-binding assays, sequencing, and fluorescence imaging. The research will shed light on the nuclear RNAi pathway and its role in human disorders.