Award
National Heart, Lung, and Blood Institute 5F31HL176049-02
The roles of Fragile-X related protein 1 in cardiomyocyte and heart biology
Recipient
University of North Carolina at Chapel Hill
Award Amount
$42,767.00
Ceiling
$42,767.00
Awarded
February 10, 2026
Identifier
5F31HL176049-02
Research project studying the role of FXR1 protein in heart biology to understand gene expression mechanisms and develop potential cardiovascular therapies.
Description
This project investigates FXR1, a protein involved in RNA processing, and its roles in heart development and physiology. The research aims to determine the translational regulation activity and protein-protein interactions of FXR1 and its striated muscle-specific forms, which will unveil mechanisms regulating gene expression in health and disease.