Award
National Institute of General Medical Sciences 5R35GM157207-02
Lysosomal membrane dynamics during stress
Recipient
Ohio State University
Award Amount
$393,750.00
Ceiling
$393,750.00
Awarded
February 10, 2026
Identifier
5R35GM157207-02
Award to Ohio State University by National Institute of General Medical Sciences for research on lysosomal membrane dynamics during stress, with a focus on LYTL and cellular responses to lysosomal damage.
Description
This project aims to elucidate lysosomal membrane dynamics under stress, focusing on LYTL's role in cellular homeostasis, responses driven by Annexin A proteins, and responses in disease-relevant cell types such as human macrophages derived from induced pluripotent stem cells.