Award
National Institute of Neurological Disorders and Stroke 4DP2NS132372-02
Uncovering brain-wide molecular determinants of individual memory performance across lifespan
Recipient
Baylor College of Medicine
Award Amount
$951,800.00
Ceiling
$951,800.00
Awarded
September 04, 2025
Identifier
4DP2NS132372-02
This award funds research to understand molecular mechanisms of memory across lifespan using Caenorhabditis elegans, aiming to identify new therapeutic targets for memory-related neurological diseases.
Description
The project aims to molecularly define memory and the mechanisms of memory performance across lifespan using cutting edge technologies in the organism Caenorhabditis elegans, which can learn and remember using the same molecules as humans. The research will generate a comprehensive molecular snapshot of mechanisms necessary for memory formation and explore strategies of variability in memory performance to predict individuals likely to exhibit improved memory with age. The work will advance understanding of neuroscience and identify new pathways and targets for therapies to prevent memory disruption due to neurological diseases.