Award
National Institute of General Medical Sciences 5R35GM130370-08
The control of gene expression by eukaryotic ribonucleases
Recipient
University of California Los Angeles, Department of Chemistry
Award Amount
$450,765.00
Ceiling
$450,765.00
Awarded
May 27, 2026
Identifier
5R35GM130370-08
This NIH-funded project investigates how eukaryotic ribonucleases control gene expression through RNA processing and degradation, focusing on nuclear ribonucleases and splicing inactivation effects.
Description
RNA processing and degradation mechanisms play critical functions in the control of gene expression. This project focuses on the function of nuclear ribonucleases and nuclear RNA degradation pathways, as well as the impact of splicing inactivation on global gene expression. The research aims to understand mechanisms by which post-transcriptional processes regulate gene expression globally.