Award
National Institute of Diabetes and Digestive and Kidney Diseases 5R01DK120921-08
Photoresponsive materials to study matricellular signaling dynamics during crypt formation and fission
Recipient
University of Colorado
Award Amount
$530,289.00
Ceiling
$530,289.00
Awarded
April 09, 2026
Identifier
5R01DK120921-08
Research project funded by NIDDK to develop photoresponsive hydrogels for studying crypt formation and fission in intestinal organoids, aiming to understand epithelial and ECM signaling in intestinal health.
Description
The project focuses on developing an in vitro model to study crypt fission in the small intestine using photoresponsive hydrogels and organoid culture. It aims to understand mechanisms of crypt formation and fission, with implications for intestinal health and disease.