Award

NIH Reporter #5R01MH126109-04

Mechanisms of Depression and Anhedonia in Adolescents: Linking Sleep Duration and Timing to Reward- and Stress-Related Brain Function

Recipient

University of Oregon, Eugene, OR

Award Amount

$743,433.00

Ceiling

$743,433.00

Awarded

December 22, 2025

Identifier

5R01MH126109-04

NIH research grant to study how sleep duration and timing affect reward and stress-related brain functions in adolescents at risk for depression, aiming to promote mental health.

Description

The long-term objectives of this proposal are: 1) to evaluate a biobehavioral model of depressive symptoms and anhedonia in adolescents, and 2) to leverage sleep and circadian function to promote mental health. The research involves observational and experimental studies assessing sleep patterns, stressful life events, and brain function related to depression and anhedonia in adolescents.

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